Team

Jonathan Heddle, Ph.D., D.Sc.
Chief Scientific Officer

Jonathan Heddle, Ph.D., DSc., is the founder and Chief Scientific Officer at nCage Therapeutics, and leads the company’s research and development activities focused on design of novel protein structures and therapeutics. Jonathan also serves as an Extraordinary Professor at the Malopolska Centre of Biotechnology (MCB), at Jagiellonian University in Krakow. Jonathan has >20 years of experience in researching natural and artificial bionanomachines. He has made significant contributions to the understanding of DNA gyrase an important antibacterial target, and has played a major role in designing novel artificial structures from DNA and proteins including nanorobotic DNA boxes, protein nanotubes and protein cages.

Prior to nCage and MCB, Jonathan carried out research at the John Innes Centre, UK and spent over a decade in Japan where he was engaged in academic teaching and investigational research, and responsible for laboratories at Tokyo Institute of Technology, and RIKEN, Japan’s largest scientific research institution.

Jonathan received his DSc. from the Institute of Biochemistry and Biophysics, Polish Academy of Sciences, his Ph.D. in Biochemistry from the University of Leicester, and a B.Pharma (Hons) from the University of Nottingham, United Kingdom.

Christopher Kaplan
Chief Executive Officer

Christopher Kaplan is the Chief Executive Officer and President of nCage Therapeutics Management Board. Chris has over 25 years of experience in the global life science industry in the development and commercialization of new therapies and technologies. Chris is also the head of Axcend Health, a biotechnology venture-building firm with offices in Boston and Warsaw.

Chris has a substantial background of experience in global life science operations, business development and licensing, and has executed numerous partnering and acquisition transactions. Chris has held significant global leadership roles at Bristol- Myers Squibb, Novartis, Boehringer Ingelheim and Sanofi.

Chris holds a Masters of Science Degree from the University of Pennsylvania, a Bachelors Degree from Columbia University, and a Management degree from the Institut Européen d’Administration des Affaires (INSEAD)

John V. Bason, Ph.D.
Chief Operating Officer

John Bason, Ph.D., is the Chief Operation Officer at nCage Therapeutics and leading the company’s operations for in the development of our novel protein cage platform and therapeutic vaccines. John also serves as a consultant to the Polish Development Fund (PFR), and is responsible for evaluating the scientific merit of the governmental fund potential investment targets.

John brings to nCage a significant background of research and development experience having worked as a Senior Investigative Scientist at the Medical Research Laboratory (MRC) in Cambridge, United Kingdom, where he was responsible for leading a series of collaborative research projects. John’s research concerned the deducting the structure and mechanism of the ATP Synthase and involved a network of international scientists in North America. John also has extensive commercial project management experience in high technology sectors in Poland and abroad.

John received his Ph.D. from Hughes Hall College, University of Cambridge, and his MBioc., in Molecular and Cellular Biochemistry from St. Hugh’s College, University of Oxford, United Kingdom.

Marcin Grudniewski
Chief Financial Officer

Marcin Grudniewski is the Chief Financial Officer at nCage Therapeutics and is responsible for all finance activities, information systems and licensing activities with global alliance partners. Marcin also acts as an investment manager at Axcend Health, a Boston and Warsaw based venture-building firm focused on the development of early-stage projects in life science.

Marcin brings experience and expertise to nCage in finance, project management and investments having worked on international and Poland based projects for financial and strategic investors.

Marcin received his Masters of Science Degree in finance and accounting from the University of Warsaw.